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Spark Holland B.V. Announces New Partnership to Increase Product Offerings, Support in North America - 21 may 2010
Pictures and presentations 2009 User Group Meeting published - 05 oct 2009
Program User Group Meeting 2009 announced - 03 jul 2009
Spark Holland Seminar Lunch ASMS 2009 - 14 may 2009
Spark Q1 figures on target for 2009 - 28 apr 2009
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Presentations
The Automation Challenge , The Automation Challenge
LC/MS: from research toy to routine tool, LC/MS: from research toy to routine tool
Recent and new development, Recent and new development
Temperature assisted eXtraxtion to reduce Ion Suppression in LC-MS analyses , Temperature assisted eXtraxtion to reduce Ion Suppression in LC-MS analyses
XLC-MS: Principles and practical applications , XLC-MS: Principles and practical applications
Optimization of the workflow in the lab., Optimization of the workflow in the lab.
Experiance with Prospekt2, Answers that matter
Latest developments in MS technology, High Throughput Quantitative Analysis by LC/MS/MS; new technology for improved productivity
Symbiosis, a new tool for increased productivity, Symbiosis, a new tool for increased productivity
Presentation European User Meeting 2004, Symbiosis: Spark’s latest developments
Presentation European User Meeting 2004, On-line SPE-LC-MS : Flexibility of Prospekt 2 device for method development and quantification of small molecules in biological fluids
Presentation European User Meeting 2004, Experiences with Symbiosis LC-MS/MS
Presentation European User meeting 2004, Prospekt in the North East of England
Presentation European User meeting 2004, Metabolomics
Presentation European User Meeting 2004, High Sensitivity Bioanalytical Methods for Peptide Drugs Using on line SPE-LC-MS/MS
Workshop European User Meeting 2004, Sorbent Screening
Workshop European User Meeting 2004, Preventive maintenance on Symbiosis Systems
Workshop European User Meeting 2004, Symbiosis, the ultimate solution to reduce carry-over to the minimum
Workshop European User Meeting 2004, Interactive Online SPE-LC-MS course on DVD, and standard LC-MS courses.
Workshop European User Meeting 2004, Symbiosis•2™ Advanced Method Development
Workshop European User Meeting 2004, Advanced quantitation approaches using Hybrid LIT LC/MS/MS technology
Workshop European User Meeting 2004, New Developments in PC control software
Presentation American User Meeting 2004, Welcome to the Spark Holland USA User Meeting!
Workshop American User Meeting 2004, From Source to Signal - Practical LC/MS/MS. An introduction to AB/SCIEX mass spectrometry products and a discussion of fundamental LC/MS/MS technologies and practices
Presentation American User Meeting 2004, Automated Method for Analyzing Antibiotics in Water
Workshop American User Meeting 2004, On-line SPE with Ion Exchange Sorbents: Develop both Sensitive and Selective Methods
Presentation American User meeting 2004, Prospekt 2: A Versatile Automation Tool for LC/MS Analysis of PK Samples
Presentation American User Meeting 2004, Symbiosis™ as a Research Tool in Drug Discovery
Presentation American User Meeting 2004, Reliance Autosampler
Presentation European Usermeeting 2005, Recent developments in Symbiosis™
Presentation European Usermeeting 2005, From Vial From Vial-to to-File File™ - A new paradigm in bioanalysis
Presentation European Usermeeting 2005, Towards an optimized bioanalytical workflow using online LC-MS/MS in drug development
Presentation European Usermeeting 2005, Strategies for identification of unknown and emerging substances in environmental samples
Presentation European Usermeeting 2005, Symbiosis a Tool For Contract Analysis
Presentation European Usermeeting 2005, Total integration of SPE into bioanalytical HPLC
Presentation European Usermeeting 2005, Experiences with Symbiosis+LC-MS/MS - method development in serum for the pg/mL region
Presentation European Usermeeting 2005, Experiences with Symbiosis LC-MS/MS - Bioanalysis in human and dog whole blood, serum and urine
Presentation European Usermeeting 2005, Using Symbiosis in LC mode
Presentation European Usermeeting 2005, Spark Application notes
Presentation European Usermeeting 2005, On-line SPE-LC-MS/MS : Quantification of Biological Markers
Presentation European Usermeeting 2005, Immuno suppressive and antiretroviral drugs
Presentation European Usermeeting 2005, Direct whole blood injection using a novel 'sorbent sampling' technique
Presentation European Usermeeting 2005, Determination of steroids using Prospekt-2 online SPE system coupled to LC-MS/MS.
Presentation European Usermeeting 2005, Strategies to fulfill carry-over requirements for LC-MS/MS analysis of biological samples
Presentation FABIAN symposium 2006, Sample prep in bio-analysis: the “last frontier” and starting point for an accurate LC-MS/MS analysis.
Presentation European Users Meeting 2007, Use of Symbiosis™ within Chemical Development
Presentation European Users Meeting 2007, Experiences with a new Symbiosis™ system in a GLP compliant bioanalytical lab
Presentation European Users Meeting 2007, High throughput applications of online SPE HPLC-MS/MS in veterinary bioanalysis.
Presentation European Users Meeting 2007, Multiresidue method for the simultaneous determination of benzimidazoles in bovine milk by online SPE-LC-MS/MS
Presentation European Users Meeting 2007, The combination of HILIC chromatography and on-line SPE-MS
Presentation European Users Meeting 2007, BLOODLYSER®: a unique solution of processing whole blood for direct SPE-LC analysis
Presentation European Users Meeting 2007, High Throughput Analysis of Amphetamines in Urine with On-line-Solid Phase Extraction-Liquid-Chromatography-Tandem Mass Spectrometry
Presentation European Users Meeting 2007, Analytics in a clinical laboratory with a Symbiosis Pharma System
Presentation European Users Meeting 2007, Quantitation of drug in human plasma at the picogram level (or lower!) using a fully automated on-line Solid Phase Extraction (SPE) coupled to liquid chromatography tandem mass spectrometry
Presentation European Users Meeting 2007, Method Development for Determination of a Pharmaceutical Drug in Animal K2EDTA-plasma using On-Line Solid Phase Extraction and LC with Mass Spectrometric Detection
Presentation European Users Meeting 2007, Determination of Aldosterone in Plasma by HPLC On-Line Solid Phase Extraction Coupled to Tandem Mass Spectrometry
Presentation European Users Meeting 2007, Automated Chromatographie Analysis in the clinical laboratory and in clinical toxicology
Presentation European Users Meeting 2007, The measurement of urinary 5-HIAA using XLC-MS/MS
Presentation user Group meeting 2008, Does online solid phase extraction and column-switching coupled to tandem mass spectrometry still have a future in modern bioanalysis?
Presentation User Group Meeting 2008, Experiences based on the Symbiosis™ Method Development Guide
Presentation User Group Meeting 2008, The analysis of pharmacodynamic biomarkers using Symbiosis™ on-line extraction and LC-MS/MS analysis
Presentation User Group Meeting 2008, Online SPE-LC-MS/MS analysis of drugs of abuse in river and waste water and estimation of drug consumption patterns
Presentation User Group Meeting 2008, High-throughput on-line SPE-LC-MS-MS method for the simultaneous analysis of amphetamines in urine
Presentation User Group Meeting 2008, Symbiosis™ for Quantitation of therapeutic peptides
Presentation User Group Meeting 2008, Bio-stability and metabolism profiling studies of peptide hormones in biological matrices using online SPE-LC/MS
Presentation User Group Meeting 2008, In-line processing of whole blood for on-line SPE-LC analysis
Presentation User Group Meeting 2008, Possibilities of On-line Bio Affinity Solid Phase Extraction (BASPE) for high-throughput analysis with LC-MS using the Spark Symbiosis platform technology
Presentation User Group Meeting 2008, Therapeutic Drug Monitoring of Immunosuppressive Drugs Using a Newly Developed Sorbent Sampling Device
Presentation User Group Meeting 2008, Optimizing MS capacity with dual Symbiosis approach
Presentation User Group Meeting 2008, Analysis of antibiotic residues in fresh milk by online SPE-LC-MS/MS
Applications
Application Info 47, A sophisticated assay for the on-line SPE-HPLC analysis of phenolic compounds in water.
Application Info 51, Automated determination of Pyrethroid insecticides in surface water by micelle-mediated on-line SPE-HPLC.
Application Info 53, Automated determination of AMPA/Glyphosate.
Application Info 48, On-line solid phase extraction coupled to mass spectrometry. Increasing productivity of MS systems.
Application Info 55, Automatische HPLC analyses of Benzodiazepine in Serum using Online SPE
Application Info 52, Appl. Info 52
Application info 49, Fully automated on-line SPE-HPLC determination of Rabbit plasma levels of andolast
Application info 50, Direct analysis of vitamin A in serum by On0line SPE-HPLC
Generic method, Generic SPE-LC-MS
Determination of Glyphosate, AMPS, Open-File Report 01-454: Determination of Glyphosate, AMPS and Glufosinate in water
Application Info 56, Determination of Warfarin in serum by XLC-MS/MS using the Symbiosis Pharma
Application Info 57, Determination of Cortisol in serum by XLC-MS/MS using the Symbiosis Pharma
Application Info 58, Determination of Carbamazepine in serum by XLC-MS/MS using Symbiosis Pharma
Application Info 59, Determination of Salbutamol in serum by XLC-MS/MS using the Symbiosis Pharma
Application Info 60, Determination of Atorvastatin and its Ortho-, Para-Hydroxy metabolites in serum by XLC-MS using Symbiosis Pharma
Application Info 61, Determination of PAH in ground, surface and drinking water using Symbiosis™ Environ
Herbicides in water, Herbicides in water
Tricyclic Anti Depressant Drugs in Serum, Tricyclic Anti Depressant Drugs in Serum
Anti Epileptic Drugs in Serum, Anti Epileptic Drugs in Serum
Herbicides in Water (II), Herbicides in Water (II)
Tetracycline Antibotics in Raw Milk Sample, Tetracycline Antibotics in Raw Milk Sample
PAH’s in Soil, PAH’s in Soil
Cyclosporine A/D in Whole Blood, Cyclosporine A/D in Whole Blood
Determination of Lipophilic Anti-Oxidantes in Blood Plasma, Determination of Lipophilic Anti-Oxidantes in Blood Plasma
Determination of N-Methyl Carbamate Pesticides in Water, Determination of N-Methyl Carbamate Pesticides in Water
Determination of Clozapine and Desmethyl-Clozapine in Human Serum, Determination of Clozapine and Desmethyl-Clozapine in Human Serum
Determination of Caffeine in Cola, Determination of Caffeine in Cola
Determination of K+ channel opener UR-8225 in plasmatic samples, Determination of K+ channel opener UR-8225 in plasmatic samples
Macrolide Antibiotics in Serum, Macrolide Antibiotics in Serum
Urinary Catecholamines, Urinary Catecholamines
Analysis of Peptide Leukotrines, Analysis of Peptide Leukotrines
Pesticides in Water, Pesticides in Water
Triazines in Drinking Water, Triazines in Drinking Water
Phenylureas in drinking water, Phenylureas in drinking water
Various pesticides in drinking water sample, Various pesticides in drinking water sample
Well water, Well water
Analysis of Ergo Alkaloids in cattle feed, Analysis of Ergo Alkaloids in cattle feed
Application Info 72, Determination of Amphetamine and Methamphetamine in Urine by XLC-MS using Symbiosis™ Pharma
Application Info 73, Determination of PAH’s in tap water using Symbiosis™ Environ with UV-DAD detection
Application Info 74, Determination of Chloramphenicol in eggs by XLC-MS using the Symbiosis Pharma System
Application Info 75, Determination of Clofibric Acid in Serum by XLC-MS using Symbiosis™ Pharma and the new Mixed-Mode Anion Cartridge
Application Info 76, Determination of Atenolol in Serum by XLC-MS using Symbiosis™ Pharma and the new Mixed-Mode Cation Cartridge
Application info 77, Simultanious determination of Glyphosate and Glufosinate using the Symbiosis PICO system
Posters
Poster 11, High sample throughput for LC-MS/MS by automated On-line SPE-MS/MS (Pittcon 1997)
Poster 13, Automated determination of Vitamine A and E in serum by On-line SPE-HPLC (Pittcon 1997)
Poster 14, Validation of an automated assay for Vitamin A and E in serum by hyphenated SPE-HPLC (Pharmanalys 1997, Fabian 1997)
Poster 15, Automated hyphenated SPE-MS for high throughput drug analysis of biological samples (Pharmanalys 1997, Fabian 1997)
Poster 17, Multiple automated clinical assay's on a single hyphenated SPE-HPLC-UV system (Pittcon 1998)
Poster 18, Simple strategy for rapid hyphenated SPE-HPLC method development (Pittcon 1998)
Poster 19, Multi automated clinical HPLC applications using a single SPE-HPLC system (Pittcon 1998)
Poster 20, Determination of target herbicides in water at low PPT level with hyphenated SPE/LC/MS/MS (HPLC 1998)
Poster 21, New instrumentation for high-throughput LC/MS with integrated solid phase extraction (ASMS 1998)
Poster 22, Improved automated trace level determination of aromatic sulfonates in water by hyphenated SPE-HPLC (HPLC 1998)
Poster 23, Determination of the optimum SPE cartridge characteristics for high speed hyphenated SPE/(LC)/MS (HPLC 1998)
Poster 24, Dedicated SPE instrumentation and SPE cartridges for high speed SPE-LC-MS. (Pittcon 1999)
Poster 25, Automated on-line SPE method development using a dedicated system configuration. (Pittcon 1999)
Poster 26, SPE-HPLC-FLU for automated profiling of tryptophan related indoles in plasma (HPLC '99)
Poster 27, Hyphenated SPE-HPLC for the analysis of dermal formulations (HPLC '99)
Poster 28, Thermally assisted online SPE (TASPE) for HPLC and LC-MS (LC-MS 1999)
Poster 12, Automated micro-derivatization and micro-LC determination of gamma-aminobtyric acid in rat brain dialysate. (Pittcon 1997, Fabian 1997)
Poster 16, Validation of a new well-plate autosampler for HPLC and LC-MS (Commtech 1998, Pittcon 1998)
Poster 03, An Improved On-line SPE-HPLC Method
Poster 07, On-Line SPE-HPLC Determination Of Glyphosate In Water.
Poster 08, On-Line SPE-HPLC determination of Polar Pesticides and Herbicides in Water.
Poster 29, Adequate Temperature Control for fast LC Separations.
Poster 30, Generic SPE-LC-MS/MS assay protocol for fast determination of drugs in biological fluids
Poster 31, Rapid automated SPE-HPLC determination of Glyphosate and AMPA in water
Poster 32, New instrumentation for automated high-speed bioanalysis
Poster 37, Determination of Clozapine and Desmethylclozapine in serum by high throughput On-line SPE LC-MS
Poster 38, Recent developments in on-line SPE for HPLC and LC-MS in bio-analysis
Poster 40, On-line SPE-LC-MS as a platform for the fast determination of immunosuppressants in biological samples
Poster 41, Denaturing Solid-Phase Extraction for reduced protein interference
Poster 33, Thermally assisted on-line Solid Phase Extraction (TASPE) for bio-analysis
Poster 34, Thermally assisted on-line Solid Phase Extraction (TASPE)
Poster 35, New instrumentation for high speed on-line Solid Phase Extraction
Poster 36, On-line Thermally Assisted SPE-LC-MS for fast determination of Sirolimus in blood
Poster 42, On-line SPE-LC-MS as a platform for the fast determination of immunosuppressants in biological samples
Poster 43, XLC-MS: Sample Extraction and LC Separation Merged into a
Poster 44, A new concept for sample introduction in Bioanalytical LC-MS
Poster 39, Rapid development of high speed on-line Solid Phase Extraction methods for LC-MS in bioanalysis
Poster 45, XLC-MS for Therapeutic Drug Monitoring
Poster 46, Symbiosis Generic XLC-MS/MS method for fast determination of drugs in biological fluids
Poster 47, XLC-MS with Peak Focusing: High Performance Front-End Sample Preparation for Bioanalysis
Poster 48, A Novel Temperature Assisted
Poster 49, Reduced Carry-over in On-line Sample Preparation Liquid
Poster 50, On-line sample preparation LC-MS in a 21 CFR § 11 compliant
Poster 52, A Novel Temperature Assisted Extraction
Poster 53, Reduction of Carry-Over in Bioanalytical LC-MS/MS - Evaluation of Valve Wash as a Tool to Improve Autosampler Cleaning Efficency
Poster 54, Strategies to fulfill carry-over requirements for SPE-LC-MS
Poster 55, The integration of solid-phase extraction and liquid chromatography
Customer 001, Determination of lercanidipine in human plasma using automated on-line solid phase extraction combined with electrospray ionization tandem mass spectrometry
Poster 56, Determination of Warfarin in Serum using SPE-LC-MS/MS
Poster 57, The “Vial-to-File™ concept” automated SPE-LC-MS sample processing with CFR21 part 11 compliancy using Symbiosis Pharma™
Poster 58, Tandem online extraction LC-MS/MS for monitoring drug levels in combination therapy
Poster 59, Online SPE-LC-MS/MS method development: a new simple and fast clean-up approach to improve sample throughput
Poster 60, Therapeutic drug monitoring of antiretroviral drugs by automated fast online XLC-MS/MS as gold-standard technique
Poster 61, Determination of lercanidipine in human plasma using automated on-line solid-phase extraction combined with electrospray ionization tandem mass spectrometry
Customer 004, Quantitation of PYY [3-36] in Human Plasma by On-line SPE LC/MS/MS
Customer 005, Metabonomics Approaches to Profiling Biological Matrices using a Hybrid LTQ-Orbitrap Mass Spectrometer
Customer 006, Vial to File - A New Paradigm for Sample Analysis in a GLP Laboratory
Customer 007, Validation of an LC-MS/MS Method for a Schering-Plough Development Compound using the Symbiosis Pharma with Direct Addition of Internal Standard
Customer 008, Development and Validation of a Sensitive Automated On-line SPE-LC/MS/MS Method to Support Early Candidate Selection in Drug Discovery
Poster 63, Whole blood analysis by online SPE-LC-MS/MS: A new approach
Poster 64, How to determine matrix effects and extraction recovery in online solid-phase extraction – liquid chromatography – mass spectrometry
Poster 65, A systematic online SPE-LC-MS/MS method development strategy for the analysis of biological samples
Technology
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HySphere cartridges
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Solid Phase Extraction