| Authors |
Published |
Added  |
Does online solid phase extraction and column-switching coupled to tandem mass spectrometry still have a future in modern bioanalysis? |
| Gerard Hopfgartner, University Geneva, Geneva, Switzerland |
September 2008 |
01 oct 2008 |
Experiences based on the Symbiosis™ Method Development Guide |
| Tony Edge, AstraZeneca, Macclesfield, United Kingdom |
September 2008 |
01 oct 2008 |
The analysis of pharmacodynamic biomarkers using Symbiosis™ on-line extraction and LC-MS/MS analysis |
| Richard Houghton, Catarina Horro Pita, Quotient Bioresearch, Fordham, United Kingdom |
September 2008 |
01 oct 2008 |
Online SPE-LC-MS/MS analysis of drugs of abuse in river and waste water and estimation of drug consumption patterns |
| Cristina Postigo, IIQAB-CSIC, Barcelona, Spain |
September 2008 |
01 oct 2008 |
High-throughput on-line SPE-LC-MS-MS method for the simultaneous analysis of amphetamines in urine |
| Maria del Mar Ramirez Fernandez, Nationaal Instituut voor Criminalistiek en Criminologie, Brussel, Belgium |
September 2008 |
01 oct 2008 |
Symbiosis™ for Quantitation of therapeutic peptides |
| Mohammed Abrar, Covance Laboratories, harrogate, United Kingdom |
September 2008 |
01 oct 2008 |
Bio-stability and metabolism profiling studies of peptide hormones in biological matrices using online SPE-LC/MS |
| Yan Wang, Amylin, San Diego, USA |
September 2008 |
01 oct 2008 |
In-line processing of whole blood for on-line SPE-LC analysis |
| Jelena Milojkovic, Institut für Klinische Chemie, München, Germany |
September 2008 |
01 oct 2008 |
Possibilities of On-line Bio Affinity Solid Phase Extraction (BASPE) for high-throughput analysis with LC-MS using the Spark Symbiosis platform technology |
| Ria Rhemrev-Boom, Resq Lab, Nijeveen, The Netherlands |
September 2008 |
01 oct 2008 |
Therapeutic Drug Monitoring of Immunosuppressive Drugs Using a Newly Developed Sorbent Sampling Device |
| Heike Burhenne, Medizinische Hochschule Hannover, Germany |
September 2008 |
01 oct 2008 |
Optimizing MS capacity with dual Symbiosis approach |
| Chris Swaanen, Benno Ingelse, Schering-Plough, Oss, The Netherlands |
|
01 oct 2008 |
Analysis of antibiotic residues in fresh milk by online SPE-LC-MS/MS |
| Lina Kantiani, IIQAB-CSIC, Barcelona, Spain |
September 2008 |
01 oct 2008 |
Simultanious determination of Glyphosate and Glufosinate using the Symbiosis PICO system |
| Spark Holland B.V. |
|
16 jul 2008 |
Fully Automated Determination in the Low Nanogram per Liter Level of Different Classes of Drugs of Abuse in Sewage Water by On-Line Solid-Phase Extraction-Liquid Chromatography-Electrospray-Tandem Mass Spectrometry |
| Cristina Postigo, Maria J. Lopez de Alda, and Damià Barceló |
Analytical Chemistry, Vol. 80, No. 9, May 1, 2008 |
23 may 2008 |
Analysis of 17 polar to semi-polar pesticides in the Ebro river delta during the main growing season of rice by automated on-line solid-phase extraction-liquid chromatography–tandem mass spectrometry |
| Marina Kuster, Maria José López de Alda, Carlos Barata, Demetrio Raldúa, Damià Barceló |
Talanta 75 (2008) 390–401 |
23 may 2008 |
Evaluating on-line solid-phase extraction coupled to liquid chromatography–ion trap mass spectrometry for reliable quantification and confirmation of several classes of antibiotics in urban wastewaters |
| Juliana Feitosa-Felizzola, Brice Temime and Serge Chiron |
Journal of Chromatography A, Volume 1164, Issues 1-2, 14 September 2007, Pages 95-104 |
27 feb 2008 |
Advantages and limitations of on-line solid phase extraction coupled to liquid chromatography–mass spectrometry technologies versus biosensors for monitoring of emerging contaminants in water |
| Sara Rodriguez-Mozaz, Maria J. Lopez de Alda and Damià Barceló |
Journal of Chromatography A, Volume 1152, Issues 1-2, 8 June 2007, Pages 97-115 |
27 feb 2008 |
The History of Bioanalytical Method Validation and Regulation: Evolution of a Guidance Document on Bioanalytical Methods Validation |
| Vinod P. Shah |
The AAPS Journal 2007; 9 (1) Article 5 |
27 feb 2008 |
CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC⁄MS) in the rat hypothalamus |
| Frédéric Béquet, Francoise Uzabiaga, Mathieu Desbazeille, Pascal Ludwiczak, Mohamed Maftouh, Claudine Picard, Bernard Scatton and Gerard Le Fur |
European Journal of Neuroscience, Vol. 26, pp. 3458–3464, 2007 |
27 feb 2008 |
Workshop/Conference Report — Quantitative Bioanalytical Methods Validation and Implementation: Best Practices for Chromatographic and Ligand Binding Assays |
| C. T. Viswanathan, Surendra Bansal, Brian Booth, Anthony J. DeStefano, Mark J. Rose, Jeffrey Sailstad, nVinod P. Shah, Jerome P. Skelly, Patrick G. Swann and Russell Weiner |
The AAPS Journal 2007; 9 (1) Article 4 |
27 feb 2008 |
High-throughput on-line solid-phase extraction–liquid chromatography–tandem mass spectrometry method for the simultaneous analysis of 14 antidepressants and their metabolites in plasma |
| Ana de Castro, Maria del Mar Ramírez Fernandez, Marleen Laloup, Nele Samyn, Gert De Boeck, Michelle Wood, Viviane Maes and Manuel López-Rivadulla |
Journal of Chromatography A, Volume 1160, Issues 1-2, 10 August 2007, Pages 3-12 |
27 feb 2008 |
Volume Overload Cleanup: An Approach for On-Line SPE-GC, GPC-GC, and GPC-SPE-GC |
| Henk Kerkdijk, Hans G. J. Mol and Bart van der Nagel, Department of Analytical Research, TNO Quality of Life, Utrechtseweg 48, 3704 HE Zeist, The Netherlands |
Anal. Chem. 2007, 79, 7975-7983 |
02 nov 2007 |
Use of Symbiosis™ within Chemical Development |
| Dan Carrier, GlaxoSmithKline, Stevenage, United Kingdom |
European Users Meeting 2007 |
24 oct 2007 |
Experiences with a new Symbiosis™ system in a GLP compliant bioanalytical lab |
| Richard Mitchell, Pfizer Ltd, Sandwich, United Kingdom |
European Users Meeting 2007 |
24 oct 2007 |
High throughput applications of online SPE HPLC-MS/MS in veterinary bioanalysis. |
| Anja Focke-Nienhues, Intervet Innovation GmbH, Schwabenheim, Germany |
European Users Meeting 2007 |
24 oct 2007 |
Multiresidue method for the simultaneous determination of benzimidazoles in bovine milk by online SPE-LC-MS/MS |
| Frederique van Holthoon, RIKILT-Institute of Food Safety, Wageningen, The Netherlands |
European Users Meeting 2007 |
24 oct 2007 |
The combination of HILIC chromatography and on-line SPE-MS |
| Peter Vince, AstraZeneca, Macclesfield, United Kingdom |
European Users Meeting 2007 |
24 oct 2007 |
BLOODLYSER®: a unique solution of processing whole blood for direct SPE-LC analysis |
| Rosa Morello, Institute of Clinical Chemistry, Munich, Germany |
European Users Meeting 2007 |
24 oct 2007 |
High Throughput Analysis of Amphetamines in Urine with On-line-Solid Phase Extraction-Liquid-Chromatography-Tandem Mass Spectrometry |
| Maria del Mar Ramirez Fernandez, National, Institute of Criminalistics and Criminology, Brussels, Belgium |
European Users Meeting 2007 |
24 oct 2007 |
Analytics in a clinical laboratory with a Symbiosis Pharma System |
| Andreas Kortenbruck, Labor Dr. Ruranski, Ettlingen, Germany |
European Users Meeting 2007 |
24 oct 2007 |
Quantitation of drug in human plasma at the picogram level (or lower!) using a fully automated on-line Solid Phase Extraction (SPE) coupled to liquid chromatography tandem mass spectrometry |
| Corinne Emotte, Novartis Pharma AG, Basel, Switzerland |
European Users Meeting 2007 |
24 oct 2007 |
Method Development for Determination of a Pharmaceutical Drug in Animal K2EDTA-plasma using On-Line Solid Phase Extraction and LC with Mass Spectrometric Detection |
| Torleif Jonsson, AstraZeneca R&D, Mölndal, Sweden |
European Users Meeting 2007 |
24 oct 2007 |
Determination of Aldosterone in Plasma by HPLC On-Line Solid Phase Extraction Coupled to Tandem Mass Spectrometry |
| Paul Taylor, Princess Alexandra Hospital, Brisbane, Australia |
European Users Meeting 2007 |
24 oct 2007 |
Automated Chromatographie Analysis in the clinical laboratory and in clinical toxicology |
| André Scholer, University Hospital Basel, Switzerland |
European Users Meeting 2007 |
24 oct 2007 |
The measurement of urinary 5-HIAA using XLC-MS/MS |
| Helma de Jong, UMC Groningen, The Netherlands |
European Users Meeting 2007 |
24 oct 2007 |
Determination of Chloramphenicol in eggs by XLC-MS using the Symbiosis Pharma System |
| Spark Holland B.V. |
June 2007 |
28 jun 2007 |
Determination of Clofibric Acid in Serum by XLC-MS using Symbiosis™ Pharma and the new Mixed-Mode Anion Cartridge |
| Spark Holland B.V. |
June 2007 |
28 jun 2007 |
Determination of Atenolol in Serum by XLC-MS using Symbiosis™ Pharma and the new Mixed-Mode Cation Cartridge |
| Spark Holland B.V. |
June 2007 |
28 jun 2007 |
How to determine matrix effects and extraction recovery in online solid-phase extraction – liquid chromatography – mass spectrometry |
| Alex Berhitu, Emile Koster |
ASMS 2007 |
08 jun 2007 |
A systematic online SPE-LC-MS/MS method development strategy for the analysis of biological samples |
| Rob Castien, Martin Sibum, Emile Koster |
ASMS 2007 |
08 jun 2007 |
Whole blood analysis by online SPE-LC-MS/MS: A new approach |
| Otto Halmingh, Peter Ringeling, Emile Koster |
ASMS 2007 |
08 jun 2007 |
Determination of PAH’s in tap water using Symbiosis™ Environ with UV-DAD detection |
| SIA Enginyers |
May 2007 |
14 may 2007 |
Determination of Amphetamine and Methamphetamine in Urine by XLC-MS using Symbiosis™ Pharma |
| Spark Holland |
May 2007 |
14 may 2007 |
Sample prep in bio-analysis: the “last frontier” and starting point for an accurate LC-MS/MS analysis. |
| Mr. Gerard Haak |
FABIAN symposium 2006 |
31 oct 2006 |
High throughput tissue residue analysis of veterinary drugs by online spe HPLC-MS/MS coupling |
| C. Bohland, S. Grieb, S. Konopka, B. Weinmann and M. Hartmann* |
Fifth intern. Symposium on hormone and veterinary drug residue analysis |
19 jul 2006 |
Development and Validation of a Sensitive Automated On-line SPE-LC/MS/MS Method to Support Early Candidate Selection in Drug Discovery |
| Carrie Xu; Baomin Xin; Timothy Olah - Bristol-Myers Squibb Company, Lawrenceville, NJ |
ASMS 2006 |
16 jun 2006 |
Validation of an LC-MS/MS Method for a Schering-Plough Development Compound using the Symbiosis Pharma with Direct Addition of Internal Standard |
| James E. Schiller; Hui Lin; Roger N. Hayes, Ph.D.; Dirk Hiemstra; Steven Eendhuizen; Valerie Cloutier |
ASMS 2006 |
15 jun 2006 |
Metabonomics Approaches to Profiling Biological Matrices using a Hybrid LTQ-Orbitrap Mass Spectrometer |
| Petia Shipkova; Robert Langish; Emily Luk; Bethanne Warrack; Serhiy Hnatyshyn; Mark Sanders |
ASMS 2006 |
15 jun 2006 |
Vial to File - A New Paradigm for Sample Analysis in a GLP Laboratory |
| Roger N. Hayes; James E. Schiller; Hui Lin; Dirk Hiemstra; Steven Eendhuizen; Rob Castien |
ASMS 2006 |
15 jun 2006 |
Tandem online extraction LC-MS/MS for monitoring drug levels in combination therapy |
| Martin Sibum, Emile Koster, Otto Halmingh |
ASMS 2006 |
01 jun 2006 |
Online SPE-LC-MS/MS method development: a new simple and fast clean-up approach to improve sample throughput |
| Emile Koster |
ASMS 2006 |
01 jun 2006 |
Therapeutic drug monitoring of antiretroviral drugs by automated fast online XLC-MS/MS as gold-standard technique |
| Therese Koal, Alex Berhitu, Emile Koster, Martin Sibum, Volkhard Kaever |
ASMS 2006 |
01 jun 2006 |
Determination of lercanidipine in human plasma using automated on-line solid-phase extraction combined with electrospray ionization tandem mass spectrometry |
| K.Y. Kim, Y. Hur, Y.J. Lee, S.M. Han, K.H. Kim, H.S. Lee |
ASMS 2006 |
01 jun 2006 |
Quantitation of PYY [3-36] in Human Plasma by On-line SPE LC/MS/MS |
| Miryam Kadkhodayan, Martin Sibum, Kevin McCowen, Deirdre Hauser |
ASMS 2006 |
01 jun 2006 |
Liquid chromatography-(tandem) mass spectrometry for the determination of microcontaminants in environmental analysis |
| A.C. Hogenboom |
Academic Thesis 2001 |
18 jan 2006 |
Determination of lercanidipine in human plasma using automated on-line solid phase extraction combined with electrospray ionization tandem mass spectrometry |
| K.Y. Kim, Y. Hur, Y.J. Lee, S.M. Han, K.H. Kim, H.S. Lee |
Bio-Medieng Co., Ltd. |
20 dec 2005 |
Fully automated multianalyte determination of different classes of pesticides, at picogram per litre levels in water, by on-line solid-phase extraction–liquid chromatography–electrospray–tandem mass spectrometry |
| Adamantia A. Kampioti, Ana C. Borba da Cunha, Maria López de Alda and Damià Barcelo |
Analytical and Bioanalytical Chemistry (2005), Issue: Volume 382, Number 8 |
13 dec 2005 |
HPLC-SPE-NMR in pharmaceutical development: capabilities and applications |
| Martin Sandvoss, Ben Bardsley, Tony L. Beck, Emma Lee-Smith, Stephanie E. North |
Magn. Reson. Chem. 2005; 43: 762-770 |
13 dec 2005 |
Detection of Eltenac in the Horse: Identification of Phase I Metabolites in Urine by Capillary Gas Chromatography-Mass Spectrometry and the Determination of Excretion Profile by Liquid Chromatography-Mass Spectrometry |
| M. C. Dumasia, I. Morelli, P. Teale |
Chromatographia, S-115 Supll. 59, 2004 |
09 dec 2005 |
Generic solid phase extraction–liquid chromatography–tandem mass spectrometry method for fast determination of drugs in biological fluids |
| Anniek Schellen, Bert Ooms, Dick van de Lagemaat, Rob Vreeken, and William D. van Dongen |
Journal of Chromatography B, Volume 788, Issue 2 , 25 May 2003, Pages 251-259 |
29 nov 2005 |
The “Vial-to-File™ concept” automated SPE-LC-MS sample processing with CFR21 part 11 compliancy using Symbiosis Pharma™ |
| Gerard Haak, Steven Eendhuizen & Alex Berhitu |
AAPS 2005 |
31 oct 2005 |
Determination of Warfarin in Serum using SPE-LC-MS/MS |
| Steven Eendhuizen, Martin Sibum & Emile Koster |
AAPS 2005 |
30 oct 2005 |
On-line SPE-LC-MS/MS : Quantification of Biological Markers |
| Pascal Ludwiczak, Sanofi Aventis, Toulouse, France |
European Usermeeting 2005 |
23 sep 2005 |
Direct whole blood injection using a novel 'sorbent sampling' technique |
| Bert Ooms |
European Usermeeting 2005 |
23 sep 2005 |
Determination of steroids using Prospekt-2 online SPE system coupled to LC-MS/MS. |
| Cornelis Tump, M.Sc, Xendo Laboratories, The Netherlands |
European Usermeeting 2005 |
23 sep 2005 |
Strategies to fulfill carry-over requirements for LC-MS/MS analysis of biological samples |
| Emile Koster |
European Usermeeting 2005 |
23 sep 2005 |
Using Symbiosis in LC mode |
| Dr. Claudia Hartig, Schering AG, Germany |
European Usermeeting 2005 |
22 sep 2005 |
Recent developments in Symbiosis™ |
| Otto Halmingh |
European Usermeeting 2005 |
22 sep 2005 |
From Vial From Vial-to to-File File™ - A new paradigm in bioanalysis |
| Rob Castien |
European Usermeeting 2005 |
22 sep 2005 |
Towards an optimized bioanalytical workflow using online LC-MS/MS in drug development |
| Dr. Benno Ingelse, Organon, The Netherlands |
European Usermeeting 2005 |
22 sep 2005 |
Strategies for identification of unknown and emerging substances in environmental samples |
| Dr. Jaroslav Slobodnik, Environmental Institute Kos, Slovak Republic |
European Usermeeting 2005 |
22 sep 2005 |
Symbiosis a Tool For Contract Analysis |
| Dr. John Edwards, CEM Analytical Services, UK |
European Usermeeting 2005 |
22 sep 2005 |
Total integration of SPE into bioanalytical HPLC |
| Prof. Dr. Dr. Karl-Siegfried Boos, University Hospital Grosshadern, Germany |
European Usermeeting 2005 |
22 sep 2005 |
Experiences with Symbiosis+LC-MS/MS - method development in serum for the pg/mL region |
| Katja Gade, Schering AG, Germany |
European Usermeeting 2005 |
22 sep 2005 |
Experiences with Symbiosis LC-MS/MS - Bioanalysis in human and dog whole blood, serum and urine |
| Andreas Schütt, Schering AG, Germany |
European Usermeeting 2005 |
22 sep 2005 |
Spark Application notes |
| Alex Berhitu |
European Usermeeting 2005 |
22 sep 2005 |
Immuno suppressive and antiretroviral drugs |
| Prof. Dr. Volkhard Keaver and Dr. Therese Koal, Institute of Pharmacology Medical school Hannover, Germany. |
European Usermeeting 2005 |
22 sep 2005 |
Determination of PAH in ground, surface and drinking water using Symbiosis™ Environ |
| Spark Holland |
September 2005 |
01 sep 2005 |
Determination of Atorvastatin and its Ortho-, Para-Hydroxy metabolites in serum by XLC-MS using Symbiosis Pharma |
| Spark Holland |
August 2005 |
01 aug 2005 |
Determination of Salbutamol in serum by XLC-MS/MS using the Symbiosis Pharma |
| Spark Holland |
July 2005 |
01 jul 2005 |
Determination of Carbamazepine in serum by XLC-MS/MS using Symbiosis Pharma |
| Spark Holland |
June 2005 |
30 jun 2005 |
The integration of solid-phase extraction and liquid chromatography |
| O. Halmingh, P. Ringeling, E.H.M. Koster |
ASMS 2005 |
07 jun 2005 |
Strategies to fulfill carry-over requirements for SPE-LC-MS |
| E.H.M. Koster |
ASMS 2005 |
07 jun 2005 |
Determination of Cortisol in serum by XLC-MS/MS using the Symbiosis Pharma |
| Spark Holland |
May 2005 |
29 may 2005 |
Determination of Warfarin in serum by XLC-MS/MS using the Symbiosis Pharma |
| Spark Holland |
April 2005 |
29 apr 2005 |
Recent Deuelopments in On-line SPE for HPLC and LC-MS in Bioanalysis |
| Emile Koster and Bert Ooms, Spark Holland, Emmen. The Netherlands |
GUIDE TO LC-MS - LC.GC Europe, supplement, December 2001 |
25 mar 2005 |
Reduction of Carry-Over in Bioanalytical LC-MS/MS - Evaluation of Valve Wash as a Tool to Improve Autosampler Cleaning Efficency |
| Johannes Hidding, Rob van der Knaap, Emile Koster and Bert Ooms |
Pittcon 2005 |
15 mar 2005 |
A Novel Temperature Assisted Extraction |
| Peter Ringeling, Emile Koster |
AAPS 2004 |
15 nov 2004 |
Welcome to the Spark Holland USA User Meeting! |
| Rob Castien, Spark Holland, Inc. |
American User Meeting 2004 |
06 oct 2004 |
From Source to Signal - Practical LC/MS/MS. An introduction to AB/SCIEX mass spectrometry products and a discussion of fundamental LC/MS/MS technologies and practices |
| Robert Ellis Ph.D., MDS Sciex |
American User Meeting 2004 |
06 oct 2004 |
Automated Method for Analyzing Antibiotics in Water |
| Edward A. Lee, US Geological Survey |
American User Meeting 2004 |
06 oct 2004 |
On-line SPE with Ion Exchange Sorbents: Develop both Sensitive and Selective Methods |
| Michael Early, Waters Corporation |
American User Meeting 2004 |
06 oct 2004 |
Prospekt 2: A Versatile Automation Tool for LC/MS Analysis of PK Samples |
| Miryam Kadkhodayan, Ph.D., Genentech, Inc. |
American User meeting 2004 |
06 oct 2004 |
Symbiosis™ as a Research Tool in Drug Discovery |
| Jian Wang, Ph. D., Bristol-Myers Squibb |
American User Meeting 2004 |
06 oct 2004 |
Reliance Autosampler |
| Rob Castien, Spark Holland, Inc. |
American User Meeting 2004 |
06 oct 2004 |
Metabolomics |
| Prof. G.J. de Jong, Department of Biomedical Analysis |
European User meeting 2004 |
23 sep 2004 |
High Sensitivity Bioanalytical Methods for Peptide Drugs Using on line SPE-LC-MS/MS |
| Carles Celma, Ipsen |
European User Meeting 2004 |
23 sep 2004 |
Symbiosis: Spark’s latest developments |
| Emile Koster, Spark Holland B.V. |
European User Meeting 2004 |
22 sep 2004 |
On-line SPE-LC-MS : Flexibility of Prospekt 2 device for method development and quantification of small molecules in biological fluids |
| Emmanuel Bourgogne, University of Geneva, Switzerland |
European User Meeting 2004 |
22 sep 2004 |
Experiences with Symbiosis LC-MS/MS |
| Dr. Claudia Hartig, Schering AG |
European User Meeting 2004 |
22 sep 2004 |
Prospekt in the North East of England |
| Ian Anderson, Analytical and Environmental Services, Horsley, Newcastle upon Tyne |
European User meeting 2004 |
22 sep 2004 |
Sorbent Screening |
| Martin Sibum |
European User Meeting 2004 |
22 sep 2004 |
Preventive maintenance on Symbiosis Systems |
| Michel Koch, Spark Holland B.V. |
European User Meeting 2004 |
22 sep 2004 |
Symbiosis, the ultimate solution to reduce carry-over to the minimum |
| Emile Koster & Peter ringeling, Spark Holland B.V. |
European User Meeting 2004 |
22 sep 2004 |
Interactive Online SPE-LC-MS course on DVD, and standard LC-MS courses. |
|
European User Meeting 2004 |
22 sep 2004 |
Symbiosis•2™ Advanced Method Development |
| Martin Sibum & dries Vrielink, Spark Holland B.V. |
European User Meeting 2004 |
22 sep 2004 |
Advanced quantitation approaches using Hybrid LIT LC/MS/MS technology |
| Henri Snijders, Applied Biosytems |
European User Meeting 2004 |
22 sep 2004 |
New Developments in PC control software |
| Tjipke de Beer, Spark holland B.V. |
European User Meeting 2004 |
22 sep 2004 |
Reduced Carry-over in On-line Sample Preparation Liquid |
| O. Halmingh, E.H.M. Koster |
June 2004, ASMS 2004 |
10 jul 2004 |
A Novel Temperature Assisted |
| Peter Ringeling, Emile Koster |
PBA 2004 |
01 jul 2004 |
On-line sample preparation LC-MS in a 21 CFR § 11 compliant |
| T. de Beer |
June 2004 |
14 jun 2004 |
XLC-MS with Peak Focusing: High Performance Front-End Sample Preparation for Bioanalysis |
| E.H.M. Koster |
March 2004, Pittcon 2004 |
11 mar 2004 |
Symbiosis Generic XLC-MS/MS method for fast determination of drugs in biological fluids |
| Otto Halmingh, Robert Mensen, Martin Sibum |
Jun 2003 |
16 dec 2003 |
XLC-MS for Therapeutic Drug Monitoring |
| E. Koster, M. Hilhorst, B. Ooms, H. Metting and H. Niederländer |
Oct 2003 |
15 dec 2003 |
A new concept for sample introduction in Bioanalytical LC-MS |
| Martijn Hilhorst and Bert Ooms, Spark Holland and Jaap Wieling, Xendo Laboratories |
May 2003 |
14 dec 2003 |
XLC-MS: Sample Extraction and LC Separation Merged into a |
| Emile Koster, Peter Ringeling, Bert Ooms, |
May 2003 |
13 dec 2003 |
Fully automated on-line liquid chromatographic separation for pollutants in various types of aqueous samples. |
| Slobodnik J., et al. |
Analytical Chimica Acta, 268 (1992), 55-65 |
12 dec 2003 |
Fully automated sample preparation & HPLC analysis of PAHs in soil. |
| Haak G., Ham M. |
International Laboratory news, July 1994, 14 |
12 dec 2003 |
Pak bestimmung durch on-line kupplung von SPE und HPLC. |
| Zobel H., Panning H.,Nowak S |
Labor Praxis, August 1995, 28-31 |
12 dec 2003 |
Fully automated multi-residue method for trace level monitoring of polar pesticides by liquid chromatography. |
| Slobodnik J., et al. |
J. of Chromatogr., 642 (1993), 359-370 |
12 dec 2003 |
Automated measurement of pesticides in drinking water using on-line SPE, HPLC and chemometry. |
| Huen J.M., et al. |
Fresenius J. Anal. Chem., 348 (1994) 606 |
12 dec 2003 |
Validation of an automated pre-column exchange system (Prospekt) coupled to LC with diode array detection. Application to the determination of pesticides in natural waters. |
| Lacorte S., Barcelo D. |
Analytica Chimica Acta, 296 (1994) 223 |
12 dec 2003 |
Rapid screening of a large group of polar pesticides in river water by on-line trace enrichment and column liquid chromatography. |
| Liska I., et al. |
Intern. J.Environ. Anal. Chem, Vol. 47 (1992) 267 |
12 dec 2003 |
Preparation and evaluation of Immunosorbents for selective trace enrichment of phenylurea and triazine herbicides in environmental waters. |
| Pichon V., Chen L., Hennion M.C., Daniel R., Martel A., Le Goffic F., Abian J., Barcelo D. |
Anal. Chem., (1995), 67, 2451-2460 |
12 dec 2003 |
Trace-level detection and identification of polar pesticides in surface water: the SAMOS approach. |
| Brinkman U.A.Th., Slobodnik J., Vreuls J.J. |
Trends in Anal.Chem., Vol.13, no.9, (1994), 373-381 |
12 dec 2003 |
SAMOS LC: A fully automated liquid chromatographic method for trace-level monitoring of polar pesticides. |
| Brinkman U.A.Th, Lingeman. H., Slobodnik J. |
LC-GC Int., March 1994, Vol. 7 no.3, 157-163 |
12 dec 2003 |
Trace-level determination of aromatic sulfonates in water by on-line ion-pair extraction/ion-pair chromatography and their behavior in the aquatic environment. |
| Lange F.T., Wenz M., Brauch H.J. |
J. High Resol. Chromatogr., Vol. 18 April 1995 |
12 dec 2003 |
A rapid screening procedure to determine the persistent bio-accumulative potential of small organic molecules by HPLC coupled with column-switching technique. |
| Li. W., l'Empereur K.M., Lam Z. |
Poster presented at HPLC '96 |
12 dec 2003 |
Stability of organophosphorous pesticides on disposable SPE-precolumns. |
| Lacorte S., Ehresmann N., Barceló D. |
Environmental Science & Technologiy Vol. 29 1995 |
12 dec 2003 |
Automated ion-pair extraction and ion-pair chromatography - a versatile method in water analysis for the determination of highly polar micro pollutants. |
| Lange F.Th., Meier U., Wenz M., Brauch H.J. |
Acta hydrochim. Hydrobiol. 23 (1995) |
12 dec 2003 |
Analytical chemistry and the Rhine basin program. |
| Pipkin W., Hout P. van |
Analytical Chemistry Jan. 1 1997 21A-25A |
12 dec 2003 |
Evaluation of new polymeric sorbents with high specific surface areas using an on-SPE-LC system for the trace level determination of polar pesticides. |
| Guena S., Hennion M.C. |
Journal of Chromatography A 737 (1996) 15-24 |
12 dec 2003 |
On-line solid phase extraction LC using restricted access pre-columns for the analysis of s-triazines in humic-containing waters. |
| Önnerfjord P., Barceló D., Emneus J., Gorton L., Marko-Varga G. |
Journal of Chromatography A 737 (1996) 35-45 |
12 dec 2003 |
On-line analysis of raw river water for trace levels of phenolic compounds by automated solid phase extraction and column liquid chromatography. |
| Fowlis I.A., Jepson I., Vreuls J.J. |
Presented at the Brighton crop protection conference - Pests & Diseases - 1996 |
12 dec 2003 |
Improvements in the determination of organophosphorus pesticides in ground- and waste water samples from inter laboratory studies by automated on-line liquid-solid extraction followed by liquid chromatography-diode array detection. |
| Lacorte S., Barcelo B. |
Journal of chromatography A, 725 (1996) 85-92 |
12 dec 2003 |
The analysis of detergents in environmental samples by on-line concentration followed by HPLC with fluorescence detection. |
| Daniel M. |
Poster presented at Pittcon 97 |
12 dec 2003 |
The Rhine basin program |
| Hout P.J.M. van, Hupe K.P., Vallet G. |
Analytical methods & Instrumentation, Volume 2-5,1995, 208-220 |
12 dec 2003 |
On-line trace enrichment of polar pesticides or degradation products in aqueous samples: compatibility of sorbents in precolumns and analytical columns |
| Guenu S., Hennion M.C. |
Analytical methods & Instrumentation, Volume 2-5,1995, 247-253 |
12 dec 2003 |
On-line SPE-LC for screening and quantification of organophosphorus pesticides in surface water. |
| Norberg J., Slobodnik J., Vreuls R.J.J., Brinkman U.A.Th. |
Analytical methods & Instrumentation, Volume 2-5,1995, 266-276 |
12 dec 2003 |
Comparison of different sorbents for on-line SPE of pesticides and phenolic compounds from natural water followed by LC. |
| Masque N., Marce R.M., Borrull F. |
J. of Chromatography A, 793 (1998), 257-263 |
12 dec 2003 |
Performance of two immunoassays for the determination of atrazine in sea water samples as compared with on-line SPE-LC-DAD. |
| Gascon J., Oubina A., Ferrer I., Onnerfjord P., Marko-Varga G., Hammock B.D., Marco M., Barcelo D. |
Analytica Chimica Acta, 330 (1996), 41-51 |
12 dec 2003 |
Pilot survey for determination of the antifouling agent irgarol 1051 in enclosed seawater samples by a direct ELISA and SPE-LC-DAD. |
| Ferrer I., Ballesteros B., Marco M.P., Barcelo D. |
Environmental science & technology, Vol.31, No.12 (1997), 3530-3535 |
12 dec 2003 |
Rapid target analysis of microcontaminants in water by on-line single-short-column LC combined with APCI ion-trap MS. |
| Hogenboom A.C., Niessen W.M.A., Brinkman U.A.Th. |
J. of Chromatography A, 794 (1998), 201-210 |
12 dec 2003 |
Long-term monitoring of pesticides and polar transformation products in ground water using automated on-line trace-enrichment and LC-DAD. |
| Dupas S., Guenu S., Pichon V., Montiel A., Welte B., Hennion M-C. |
Intern. J. Environ. Anal. Chem., 65 (1996), 53-68 |
12 dec 2003 |
Validation of an enzymatic biosensor with various liquid chromatographic techniques for determinating organophosphorus pesticides and carbaryl in freeze-dried waters. |
| Marty J.L., Mionetto, N., Lacorte S., Barcelo D. |
Analytica Chimica Acta 311 (1995), 265-271 |
12 dec 2003 |
Evaluation of a magnetic particle-based ELISA for the determination of chlorpyrifosethyl in natural waters and soil samples. |
| Oubina A., Gascon J., Ferrer I., Barcelo D. |
Environmental Science & Technology 30 (1996), 509-512 |
12 dec 2003 |
Monitoring of organic micropollutants in surface water by automated on-line trace-enrichment liquid and gas chromatographic systems with DAD and MS detection. |
| Slobodnik J., Louter A.J.H., Vreuls J.J., Liska I.,Brinkman U.A.Th. |
J. of Chromatography A,768 (1997), 239-258 |
12 dec 2003 |
Disappearance of aerially applied fenitrothion in rice crop waters. |
| Oubina A., Ferrer I., Gascon J., Barcelo D. |
Environ.Sci.Technol. 30 (1996), 3551-3557 |
12 dec 2003 |
Monitoring of pesticides in river water using fully automated on-line SPE and LC with DAD with a novel filtration device. |
| Lacorte S., Vreuls J.J., Salau J.S., Ventura F., Barcelo D. |
J. of Chromatography A,795 (1998), 71-82 |
12 dec 2003 |
Automation in multiresidue analysis of pesticides using on-line solid-phase extraction and liquid chromatography. |
| Hennion M.-C. |
Analusis magazine, 26, No 6(1998), m131-m137 |
12 dec 2003 |
Application of an on-line liquid chromatographic system for the determination of polar herbicides in drinking water within a routine laboratory. |
| Mills G.R. |
J. of Chromatography A, 813(1998), 63-70 |
12 dec 2003 |
Application of multivariate self-modeling curve resolution to the quantitation of trace levels of organophosphorus pesticides in natural waters from interlaboratory studies. |
| auler R., Lacorte S. and Barcelo D. |
J Chromatogr. A, 730(1996), 177-183 |
12 dec 2003 |
Trace-level determination of pesticide residues using on-line SPE-LC with atmospheric pressure ionization mass spectrometric and tandem mass spectrometric detection. |
| Slobodnik J., Hogenboom A.C., Vreuls J.J., Rontree J.A., van Baar B.L.M., Niessen W.M.A. and Brinkman U.A.Th. |
J. Chromatogr. A, 741(1996), 59-74 |
12 dec 2003 |
Rapid target analysis by on-line single short column liquid chromatography /thermospray tandem mass spectrometry. |
| Minnaard W.A., Hogenboom A.C., Malmquist U.K., Manini P., Niessen W.M.A., Brinkman U.A.Th. |
Rapid communications in mass spectrometry, vol 10 1569-1574 (1996) |
12 dec 2003 |
Integrated system for on-line gas and liquid chromatography with a single mass spectrometric detector for the automated analysis of environmental samples. |
| Slobodnik J., Hogenboom A.C., Louter A.J.H., Brinkman U.A.Th. |
Journal of chromatography A 730 (1996) 353-371 |
12 dec 2003 |
Determination and stability of pesticides in freeze-dried extraction water samples by automated on-line SPE followed by LC with diode-array detection. |
| Ferrer I., Barceló D. |
Journal of chromatography A 737 (1996) 93-99 |
12 dec 2003 |
Degradation of organophosphous pesticides and their transformation products in estuarine water. |
| Lacorte S., Lartiges S.B., Garrigues P., Barceló D. |
Environmental Science & Technology Vol. 29 1995, 431-438 |
12 dec 2003 |
Rapid target analysis of micro-contaminants in water by on-line single-short-column liquid chromatography combined with atmospheric pressure chemical ionization tandem mass spectrometry. |
| Hogeboom A.C., Speksnijder P, Vreeken R.J., Niessen W.M.A., Brinkman U.A.Th. |
Journal of Chromatography A, 777 (1997) 81-90 |
12 dec 2003 |
On-line trace level determination of polar organic micro-contaminants in water using various pre-column-analytical column LC techniques with UV absorbance and MS detection. |
| Hogenboom A.C., Jagt I., Vreuls R.J.J., Brinkman U.A.Th. |
Analyst, November 1997, 122, 1371-1377 |
12 dec 2003 |
Determination of pesticides by on-line trace enrichment reversed-phase LC-DAD and confirmation by particle-beam MS. |
| Aguilar C., Borrull F., Marce R.M. |
Chromatographia, Vol.43, No.11/12, December 1996, 592-598 |
12 dec 2003 |
Rapid target analysis of microcontaminants in water by on-line single-short-column liquid chromatography combined with atmospheric pressure chemical ionization tandem mass spectrometry. |
| Hogenboom A.C., Speksnijder P., Vreeken R.J., Niessen W.M.A., Brinkman U.A.Th.. |
J. of Chromatography A, 777 (1997), 81-90 |
12 dec 2003 |
Rapid target analysis of microcontaminants in water by on-line single-short-column LC combined with APCI ion-trap MS. |
| Hogenboom A.C., Niessen W.M.A., Brinkman U.A.Th. |
J. of Chromatography A, 794 (1998), 201-210 |
12 dec 2003 |
Drying agents for water-free introduction of desorption solvent into a GC after on-line SPE of aqueous samples. |
| Pico. Y., et al. |
Chromatographia,38: 7/8 (1994), 461-469 |
12 dec 2003 |
Analysis of micro-contaminants in aqueous samples by fully automated on-line SPE-GC-MSD. |
| Louter A.J.H., van Beekvelt C.A., Cid Montanes P., Slobodnik J., Vreuls J.J., Brinkman U.A.Th. |
J. of Chromatogr. A, Feb (1996) 76-83 |
12 dec 2003 |
On-line solid phase extraction-gas chromatography-cryotrapping-infrared spectrometry for the trace-level determination of microcontaminants in aqueous samples. |
| Hankemeier T., Hooijschuur E., Vreuls R.J.J., Brinkman U.A.Th. |
J. High Resol. Chromatogr. 21 (1998), 341-346 |
12 dec 2003 |
Fully automated water analyser based on on-line solid-phase extraction-gas chromatography. |
| Louter A.J.H., Brinkman U.A.Th., Ghijsen R.T. |
J. Microcolumn Sep. 5 (1993), 303-315 |
12 dec 2003 |
Open-File Report 01-454: Determination of Glyphosate, AMPS and Glufosinate in water |
| U.S. Geological Survey, E.E. Lee, A.P. Strahan and E.M. Truman |
2002 |
12 dec 2003 |
Fully automated sample handling system for liquid chromatography based on pre-column technology and automated cartridge exchange. |
| Nielen M.W.F., Valk A.J., Frei R.W., Brinkman U.A.Th |
J. of Chromatography, 393 (1987), 69-83. |
12 dec 2003 |
Automated SPE and sample preparation - finding the right solution for your laboratory. |
| Smith G.A., Lloyd T.L |
LC-GC, current trends and developments in sample prep., may 1998, 22-31 |
12 dec 2003 |
A review of modern solid-phase extraction. |
| Majors R.E |
LC-GC, current trends and developments in sample prep., may 1998, 8-15 |
12 dec 2003 |
High sample throughput for LC-MS/MS by automated on-line SPE-MS/MS. |
| Ooms J.A., Haak G.S.J., Halmingh O. |
International laboratory news, december 1997 |
12 dec 2003 |
On-line SPE-LC-MS as a platform for the fast determination of immunosuppressants in biological samples |
| Emile Koster, Bert Ooms, Johan Hoesen, Harm Niederländer |
Nov 2002 |
12 dec 2003 |
Generic SPE-LC-MS |
| Otto Halmingh, Robert Mensen, MArtin Sibum, Marcel Jansen, Spark Holland B.V. |
Sep 2003 |
12 dec 2003 |
Determination of ketorolac in human plasma by high performance liquid chromatography after automated on-line solid phase extraction. |
| Sola J., Prunonosa J., Colom H., Peraire C., Obach R. |
J. Liq. Chromatogr. Relat. Technology (1996), 19(1), 89-99 |
12 dec 2003 |
Analysis of serotonin in whole blood samples - A novel fully automated method. |
| Opper C., et al |
LC-GC (1994), 12(9), 684-698 |
12 dec 2003 |
On-line fully automated determination of clozapine in human serum by SPE on exchangeable cartridges and LC using a methanol buffer on unmodified silica. |
| Olesen O.,Poulsen B. |
J. of Chromatogr., Biomed. Applic., 622, (1993), 39-46 |
12 dec 2003 |
Application of totally automated on-line sample clean up for prostanoid extraction and HPLC separation. |
| Hotter G., et al. |
Chromatographia, 36 (1993), 33-38 |
12 dec 2003 |
Automated analysis of urinary catecholamines by HPLC and on-line pretreatment. |
| Pastoris A., Caruuti L., Sacco R., Da Vecchi L., Shaffi A. |
J. of Chromatogr., 664 (1995), 287-293 |
12 dec 2003 |
LC determination of the macrolide antibiotics roxithromycin and clarithromycin in plasma by SPE and electrochemical detection. |
| Hedenmo M., Eriksson B.M. |
J. of Chromatography A, 692 (1995) 161-166 |
12 dec 2003 |
Determination of the anti-platelet-activating factor BN-50727 and metabolites in human urine by SPE. |
| Prunonosa J., Sola J., Peraire F., Lavergne R., Obach R. |
J. of Chromatog. B, 677 (1996) 388-392 |
12 dec 2003 |
Automated HPLC assay for lsopitron, a novel anxiolytic, in human plasma using on-SPE. |
| Garcia-Encina G., Farran R., Puig S., Serafini M.T., Martinez L. |
J. of Chromatog. B, 670 (1995) 103-110 |
12 dec 2003 |
On-line SPE with automated cartridge exchange for LC determination of lipophilic antioxidants in plasma. |
| Hedenmo M., Eriksson B.M. |
Journal of chromatography A, 661 (1994) 153 - 159 |
12 dec 2003 |
Direct determination of anabolic steroids in human urine by on-line SPE/LC/MS. |
| Barron D., Barbosa J., Pascual J.A., Segura J. |
J. of Mass Spectrometry, 31 (1996), 309-319 |
12 dec 2003 |
Evaluation of an on-line SPE method for determination of almokalant. An anti-arrhythmic drug, by LC. |
| Svennberg H., Lagerstrom P. |
J. of Chromatography B, 689 (1997), 371-377 |
12 dec 2003 |
LC determination of fluvastatin and its enantiomers in blood plasma by automated SPE |
| Toreson H., Eriksson B.-M. |
Chromatographia, Vol.45 (1997), 29-34 |
12 dec 2003 |
Determination of Pranlukast and its metabolites in human plasma by LC/MS/MS with PROSPEKT TM on-line solid-phase extraction. |
| Marches A., McHugh C., Kehler J., Bi H. |
J. Mass Spectrom 33 (1998), 1071-1079 |
12 dec 2003 |
On-line fully automated SPE/LC analysis of 1,2-dihydro-4-(1,2-dihydro-2-oxo-1-pyridyl)-2,2-dimethyl-1-oxonaphthalene-6-carbonitrile (UR-8225), a new potassium channel opener, in plasma samples. |
| Nieto C., Ramis J., Conte L. Fernandez J.M., Forn J. |
J. of Chromatography B, 661 (1994), 319-325 |
12 dec 2003 |
Determination of the anti-platelet-activating factor BN-50727 and its metabolites in human plasma by HPLC/SPE. |
| Prunonosa J., Parera L., Peraire C., Pla F., Lavergne O., Obach R. |
J. of Chromatography B, 668 (1995), 281-290 |
12 dec 2003 |
Evaluation of tamoxifen and a-hydroxytamoxifen 32P-post-labelled DNA adducts by the development of a novel automated on-line solid-phase extraction HPLC method. |
| Martin E.A., Heydon R.T., Brown K., Brown J.E., Lim C.K., White I.N.H., Smith L.L. |
Carcinogenesis (1998),19(6), 1061-1069 |
12 dec 2003 |
Validation of an automated assay for vitamins A and E in serum by SPE-HPLC. |
| Halmingh O., van Gils M., Ooms B. |
American Clinical Laboratory, jan/feb 1999, 6-7 |
12 dec 2003 |
Piroxicam quantitation in human plasma by high-performance liquid chromatography with on- and off-line solid-phase extraction. |
| Yritia M., Parra P., Fernandez J.M., Barbanoj J.M. |
J. of Chromatography A, 846(1999), 199-205 |
12 dec 2003 |
Determination of N-methylcarbamate pesticides in environmental water samples using automated on-line trace enrichment with exchangeable cartridges and HPLC. |
| Hiemstra M., de Kok A. |
J. of Chromatography A, 667(1994), 155-166 |
12 dec 2003 |
In vivo pharmacokinetic screening in cassette dosing experiments: the use of on-line Prospekt LC-APCI-MS/MS technology in drug discovery. |
| Beaudry F., Le Blanc J.C.Y., Coutu M., Brown N.K. |
Rapid Commun. Mass Spectrom. 12(1998), 1216-1222 |
12 dec 2003 |
HPLC method for the simultaneous determination of the camptothecin derivate irinotecan hydrochloride, CPT-11, and its metabolites SN-38 and SN-38 glucurone in rat plasma with a fully automated on-line SPE system, Prospekt. |
| Kurita A., Kaneda N. |
J. Chromatogr. B, 724(1999), 335-344 |
12 dec 2003 |
Fully automated analytical method for codeine quantification in human plasma using on-line SPE and HPLC with UV detection. |
| Pascual J.A., Sanagustin J. |
J. Chromatogr. B, 724(1999), 295-302 |
12 dec 2003 |
A direct technique for the simultaneous determination of 10 drug candidates in plasma by LC-API-MS/MS. |
| McLoughlin D.A., Olah T.V., Gilbert J.D. |
Journal of Pharmaceutical and Biomedical Analysis 15 (1997) 1893-1901 |
12 dec 2003 |
Automated SPE and tandem MS without HPLC columns for quantifying drugs at the picogram level. |
| Bowers G.P., Clegg S.C., Hughes S.C., Harker A.J., Lambert S. |
LC-GC vol. 15 no.1`Jan. 1997 |
12 dec 2003 |
In vivo pharmacokinetic screening in cassette dosing experiments: the use of on-line Prospekt LC-APCI-MS/MS technology in drug discovery. |
| Beaudry F., Le Blanc J.C.Y., Coutu M., Brown N.K. |
Rapid Commun. Mass Spectrom. 12(1998), 1216-1222 |
12 dec 2003 |
Denaturing Solid-Phase Extraction for reduced protein interference |
| Emile Koster, Peter Ringeling, Bert Ooms |
Mar 2003 |
11 dec 2003 |
On-line SPE-LC-MS as a platform for the fast determination of immunosuppressants in biological samples |
| Emile Koster, Bert Ooms, Johan Hoesen, Harm Niederländer |
May 2002 |
10 dec 2003 |
Rapid development of high speed on-line Solid Phase Extraction methods for LC-MS in bioanalysis |
| Dries Vrielink, Anniek Schellen, Emile Koster and Bert Ooms |
Mar 2002 |
09 dec 2003 |
Recent developments in on-line SPE for HPLC and LC-MS in bio-analysis |
| Emile Koster and Bert Ooms |
Jun 2001 |
08 dec 2003 |
Determination of Clozapine and Desmethylclozapine in serum by high throughput On-line SPE LC-MS |
| M.J. Hilhorst, E.H.M. Koster, J.A. Ooms, H.A.G. Niederländer and G.J. de Jong |
Jun 2001 |
07 dec 2003 |
On-line Thermally Assisted SPE-LC-MS for fast determination of Sirolimus in blood |
| Emile Koster, Bert Ooms, Harm Niederländer, Ad de Jong |
May 2001 |
06 dec 2003 |
New instrumentation for high speed on-line Solid Phase Extraction |
| Emile Koster, Dries Vrielink and Bert Ooms |
Mar 2001 |
05 dec 2003 |
Thermally assisted on-line Solid Phase Extraction (TASPE) |
| Emile Koster and Bert Ooms |
Mar 2001 |
04 dec 2003 |
Thermally assisted on-line Solid Phase Extraction (TASPE) for bio-analysis |
| Emile Koster, Gerard Haak and Bert Ooms |
Feb 2001 |
03 dec 2003 |
New instrumentation for automated high-speed bioanalysis |
| Otto Halmingh, Dries Vrielink, Gerard Haak |
Feb 2001 |
02 dec 2003 |
Rapid automated SPE-HPLC determination of Glyphosate and AMPA in water |
| Dries Vrielink, Otto Halmingh, Mark van Gils and Bert Ooms, |
Jun 2000 |
01 dec 2003 |
Generic SPE-LC-MS/MS assay protocol for fast determination of drugs in biological fluids |
| Anniek Schellen, Bert Ooms, Mark van Gils and Otto Halmingh,Dick van de Lagemaat, William van Dongen, 7800 AJ Emmen, The Netherlands. |
May 2000 |
30 nov 2003 |
Adequate Temperature Control for fast LC Separations. |
| Dries Vrielink, Michiel Godschalk, Mark van Gils, Bert Ooms, |
Mar 2000 |
29 nov 2003 |
Thermally assisted online SPE (TASPE) for HPLC and LC-MS (LC-MS 1999) |
| Alida Duinkerken, Anniek Schellen, Otto Halmingh, Mark van Gils and Bert Ooms |
Oct 1999 |
28 nov 2003 |
Hyphenated SPE-HPLC for the analysis of dermal formulations (HPLC '99) |
| M. Krämer, A. Moyon, O. Halmingh , J. A. Ooms |
May 1999 |
27 nov 2003 |
SPE-HPLC-FLU for automated profiling of tryptophan related indoles in plasma (HPLC '99) |
| I.E. Kema, G. Meiborg, O. Halmingh and J.A. Ooms |
Mar 2000 |
26 nov 2003 |
Automated on-line SPE method development using a dedicated system configuration. (Pittcon 1999) |
| O. Halmingh, G. J. M. van Gils, A.R. Duinkerken, J.A. Ooms |
May 1999 |
25 nov 2003 |
Dedicated SPE instrumentation and SPE cartridges for high speed SPE-LC-MS. (Pittcon 1999) |
| Anniek Schellen, Bert Ooms, Mark van Gils , Otto Halmingh |
Jun 1999 |
24 nov 2003 |
Determination of the optimum SPE cartridge characteristics for high speed hyphenated SPE/(LC)/MS (HPLC 1998) |
| O. Halmingh, G.J.M. van Gils, J.A. Ooms |
Nov 1998 |
23 nov 2003 |
Improved automated trace level determination of aromatic sulfonates in water by hyphenated SPE-HPLC (HPLC 1998) |
| T. Landrieux, F.Th. Lange, M. Wenz, H.-J. Brauch, O. Halming, J.A. Ooms |
Apr 1998 |
22 nov 2003 |
New instrumentation for high-throughput LC/MS with integrated solid phase extraction (ASMS 1998) |
| O. Halmingh, G.J.M. van Gils, J.A. Ooms |
May 1998 |
21 nov 2003 |
Determination of target herbicides in water at low PPT level with hyphenated SPE/LC/MS/MS (HPLC 1998) |
| L. Maljers O. Halmingh, J.A. Ooms, G.S.J. Haak |
Nov 1998 |
20 nov 2003 |
Multi automated clinical HPLC applications using a single SPE-HPLC system (Pittcon 1998) |
| O. Halmingh, G.J.M. van Gils, J.A. Ooms |
Feb 1998 |
19 nov 2003 |
Simple strategy for rapid hyphenated SPE-HPLC method development (Pittcon 1998) |
| O. Halmingh, J.A. Ooms |
Feb 1998 |
18 nov 2003 |
Multiple automated clinical assay's on a single hyphenated SPE-HPLC-UV system (Pittcon 1998) |
| O. Halmingh, G.J.M. van Gils, J.A. Ooms |
Feb 1998 |
17 nov 2003 |
Validation of a new well-plate autosampler for HPLC and LC-MS (Commtech 1998, Pittcon 1998) |
| M.H. Godschalk, S. Vonk and J.A. Ooms |
Jan 1998 |
16 nov 2003 |
Automated hyphenated SPE-MS for high throughput drug analysis of biological samples (Pharmanalys 1997, Fabian 1997) |
| J.A. Ooms, G.S.J. Haak, O. Halmingh |
Oct 1997 |
15 nov 2003 |
Validation of an automated assay for Vitamin A and E in serum by hyphenated SPE-HPLC (Pharmanalys 1997, Fabian 1997) |
| O. Halmingh, G.J.M. van Gils, J.A. Ooms |
Feb 1998 |
14 nov 2003 |
Automated determination of Vitamine A and E in serum by On-line SPE-HPLC (Pittcon 1997) |
| O.Halmingh, H. Kerkdijk, G.J.M. van Gils |
Mar 1997 |
13 nov 2003 |
Automated micro-derivatization and micro-LC determination of gamma-aminobtyric acid in rat brain dialysate. (Pittcon 1997, Fabian 1997) |
| M.H. Godschalk, A.J. Voerman, J.A. Ooms |
Mar 1997 |
12 nov 2003 |
High sample throughput for LC-MS/MS by automated On-line SPE-MS/MS (Pittcon 1997) |
| J.A. Ooms, G.S.J. Haak, O. Halmingh |
Mar 1997 |
11 nov 2003 |
On-Line SPE-HPLC determination of Polar Pesticides and Herbicides in Water. |
| O.Halmingh, H. Kerkdijk, J.A. Ooms |
Mar 1997 |
08 nov 2003 |
On-Line SPE-HPLC Determination Of Glyphosate In Water. |
| H. Kerkdijk, M.H. Godschalk, O. Halmingh |
Mar 1997 |
07 nov 2003 |
An Improved On-line SPE-HPLC Method |
| O. Halmingh, H. Kerkdijk |
Mar 1997 at HPLC'97 |
03 nov 2003 |
The Automation Challenge |
| Rob Castien, Spark Holland. |
Usermeeting 2003 |
22 oct 2003 |
LC/MS: from research toy to routine tool |
| Andries Bruins, University of Groningen |
Usermeeting 2003 |
22 oct 2003 |
Recent and new development |
| Jaap Wielinga, XENDO Laboratories |
Usermeeting 2003 |
22 oct 2003 |
Temperature assisted eXtraxtion to reduce Ion Suppression in LC-MS analyses |
| Emile Koster |
Usermeeting 2003 |
22 oct 2003 |
XLC-MS: Principles and practical applications |
| Emile Koster, Spark Holland |
Usermeeting 2003 |
22 oct 2003 |
Optimization of the workflow in the lab. |
| Benno Ingelse, Organon |
Usermeeting 2003 |
22 oct 2003 |
Answers that matter |
| Xavier Taillieu, Lilly Research Laboratories |
Usermeeting 2003 |
22 oct 2003 |
High Throughput Quantitative Analysis by LC/MS/MS; new technology for improved productivity |
| Henri Snijders, Applied Biosystems. |
Usermeeting 2003 |
22 oct 2003 |
Symbiosis, a new tool for increased productivity |
| Gerard Haak, Spark Holland |
Usermeeting 2003 |
22 oct 2003 |
Analysis of Ergo Alkaloids in cattle feed |
| Spark Holland |
|
01 jan 2003 |
Anti Epileptic Drugs in Serum |
| Spark Holland |
|
01 jan 2003 |
Analysis of Peptide Leukotrines |
| Spark Holland |
|
01 jan 2003 |
Herbicides in Water (II) |
| Spark Holland |
|
13 mar 2000 |
PAH’s in Soil |
| Spark Holland |
|
13 mar 2000 |
Determination of N-Methyl Carbamate Pesticides in Water |
| Spark Holland |
|
13 mar 2000 |
Pesticides in Water |
| Spark Holland |
|
13 mar 2000 |
Triazines in Drinking Water |
| Spark Holland |
|
13 mar 2000 |
Phenylureas in drinking water |
| Spark Holland |
|
13 mar 2000 |
Various pesticides in drinking water sample |
| Spark Holland |
|
13 mar 2000 |
Well water |
| Spark Holland |
|
13 mar 2000 |
Tetracycline Antibotics in Raw Milk Sample |
| Spark Holland |
|
13 mar 2000 |
Determination of Caffeine in Cola |
| Spark Holland |
|
13 mar 2000 |
Tricyclic Anti Depressant Drugs in Serum |
| Spark Holland |
|
13 mar 2000 |
Determination of Lipophilic Anti-Oxidantes in Blood Plasma |
| Spark Holland |
|
13 mar 2000 |
Determination of Clozapine and Desmethyl-Clozapine in Human Serum |
| Spark Holland |
|
13 mar 2000 |
Macrolide Antibiotics in Serum |
| Spark Holland |
|
13 mar 2000 |
Urinary Catecholamines |
| Spark Holland |
|
13 mar 2000 |
Herbicides in water |
| Spark Holland |
|
10 mar 2000 |
Determination of K+ channel opener UR-8225 in plasmatic samples |
| Spark Holland |
|
01 mar 2000 |
Automatische HPLC analyses of Benzodiazepine in Serum using Online SPE |
| Spark Holland |
Oct 1998 |
25 feb 2000 |
Automated determination of AMPA/Glyphosate. |
| Spark Holland |
Aug 1996 |
23 feb 2000 |
Appl. Info 52 |
| Spark Holland |
Jun 1996 |
22 feb 2000 |
Automated determination of Pyrethroid insecticides in surface water by micelle-mediated on-line SPE-HPLC. |
| Spark Holland |
Jun 1996 |
21 feb 2000 |
Direct analysis of vitamin A in serum by On0line SPE-HPLC |
| Spark Holland |
Aug 1995 |
20 feb 2000 |
Fully automated on-line SPE-HPLC determination of Rabbit plasma levels of andolast |
| Spark Holland |
Dec 1996 |
19 feb 2000 |
On-line solid phase extraction coupled to mass spectrometry. Increasing productivity of MS systems. |
| Spark Holland |
Sep 1995 |
18 feb 2000 |
A sophisticated assay for the on-line SPE-HPLC analysis of phenolic compounds in water. |
| Spark Holland |
|
17 feb 2000 |
Cyclosporine A/D in Whole Blood |
| Spark Holland |
Apr 1997 |
01 jan 2000 |
